MU researchers discover protein's ability to inhibit HIV release

One of the largest universities in the United States, The Ohio State University is a leading research university and the model for the state of Ohio's public higher education institutes.  Founded in 1870 as a land-grant university, it was ranked in 2006 as one of the top 20 public universities in the United States.  The main campus is located in Columbus, and regional campuses are located in Lima, Mansfield, Marion, Newark and Wooster.

The Ohio State University

Professor Liu studies virus-host interactions, in particular how RNA viruses enter host cells and cause pathogenesis in humans and animals. While in the past the Liu lab has been mainly focusing on retroviruses, including HIV, current efforts also include some new human emerging and re-emerging infectious diseases, such as Ebola and Zika. Rotation and research projects include a better understanding the molecular process by which RNA viruses enter host cells or fuse with them, as well as developing effective ways to deliver human gene therapy. The Liu lab also studies some interferon-stimulated genes (ISGs), including IFITM, Viperin and Tetherin, with an ultimate goal of developing effective therapeutic strategies. Another aspect of Liu lab research is viral oncology, with major efforts in elucidating how some viral oncogenes induce oncogenic transformation leading to cancer as well as discovering new tumor viruses that could be associated with human lung and other epithelial cancers.

Viral Infections

Ebola

Lung Cancer

Cancer Biology

Cell Biology

Virology

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Researchers discover protein's ability to inhibit HIV release

Professor I Department of Veterinary Biosciences

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